Schedule¶
| Day | Time | Room | Topic |
|---|---|---|---|
| Day 1 Sep. 2nd |
14:30-18:00 | Waalbrug B | 🧬 Computational immunity |
| Day 2 Sep. 3rd |
9:30-16:30 | Waalbrug B (main) De Oversteek (parallel talk) |
🤖 Geometric deep learning & 3D modelling + outing |
| Day 3 Sep. 4th |
9:30-17:35 | Auditorium | 🔬 T-cell immunity and therapy |
Day 1: Computational Immunity (Room: Waalbrug B)¶
| Time | Event |
|---|---|
| 14:30-15:00 | 📋 RegistrationRegister and coffee |
| 15:00-15:05 | 🎯 OpeningOpening |
| 15:05-16:30 |
🎤 Invited TalksInvited talks (20+5 min/talk): Session chairs: Johannes Textor, Dario Marzella
David Gfeller (UNIL) Predicting TCR-peptide-MHC interactions - How can we bridge the two sides of the equation
Vincent Zoete (UNIL) Computer-aided Molecular Engineering
Li Xue (Radboudumc)
AI-boosted 3D modelling for cancer immunotherapy
|
| 16:30-17:00 | ☕ BreakCoffee break, snacks |
| 17:00-17:45 |
⚡ Flash TalksFlash talks (12+3 min/talk): Session chair: Li Xue
Cunliang Geng (NLeSc) DeepRank2 - a python framework for mining 3D protein structures with geometric deep learning
Chris Thorpe (EBI) Experiments in generating Multiple Sequence Alignments for AlphaFold which include specific co-evolutionary information for MHC:peptide complexes
Mihaela Mihaylova (Radboud)
Human-in-the-loop approach for less laborious cell tracking
|
Day 2: AI and 3D modelling (Room: Waalbrug B)¶
| Time | Event |
|---|---|
| 9:30-10:00 | 📋 RegistrationRegister/coffee |
| 10:00-10:45 |
⚡ Parallel Flash TalksParallel flash talks (Two rooms, 12+3 min/talk): ⭐ AI on 3D (Room: Waalbrug B): Session chairs: Erik Bekkers, Cong Liu
David Frühbuß (Max Planck) MHC-Diff: Fast and Accurate Peptide–MHC Structure Prediction via an Equivariant Diffusion Model
Rens den Braber (UvA) AI-based energy predictor for conformation sampling
Amelia Villegas-Morcillo (TU Delft) All-atom and structure-aware generative design of immunoproteins using diffusion models
🌟 AI on 3D (Room: De Oversteek): Session chair: Daniel Rademaker
Farzaneh Meimandi parizi (Radboud) SwiftTCR: Efficient computational docking protocol of TCRpMHC-I complexes using restricted rotation matrices
Dario Marzella (Radboudumc) Improving peptide-MHC binding prediction through structure-based AI models
Riza Özçelik (TU/e)
Look the Other Way: Designing 'Positive' Molecules with Negative Data via Task Arithmetic
|
| 10:45-11:15 | ☕ BreakCoffee break |
| 11:15-12:05 |
🎤 Invited TalksInvited talks (Room: Waalbrug B, 20+5 min/talk): Session chairs: Martijn Huijnen, Dario Marzella
Johannes Textor (Radboud University) How T cells coordinate their motion in single lane traffic
Yang Yang (Shanghai Jiaotong Univ)
EPIC: Multi-objective Guided Diffusion for Epitope Design in TCR-pMHC Complexes
|
| 12:05-13:30 | 🍽️ LunchLunch and poster session |
| 13:30-14:45 |
🎤 Invited Talks Geometric deep learning (20+5 min/talk): Session chair: Li Xue
Erik Bekkers (UvA) Equivariance and weight-sharing in neural networks without specialized modules
Artem Moskalev (Johnson&Johnson) Language and Geometry models for RNA
Cong Liu (UvA)
Geometric Modelling with Clifford Algebra for Molecules and Proteins
|
| 14:45-15:15 | ☕ BreakCoffee break |
| 15:15-16:30 |
🎤 Invited Talks3D modelling and design (20+5 min/talk): Session chairs: Hanka Venselaar, Coos Baakman
Monica Fernandez-Quintero (Scripps) Structure and dynamics-guided antibody design
Hashem Koohy (Oxford) Decoding Antigen Recognition Through Structural Modelling of TCR:pMHC complexes
Danny Sahtoe (Hubrecht Institute)
Design of conformational and epigenetic control systems
|
| 17:15-19:15 | Outing - Historical walk of Nijmegen (starting point: Central Station Nijmegen) |
| 19:30 | Dinner with speakers and organizers @ Waagh restaurant (invitation only) |
Day 3: T cell immunity and therapy (Room: Auditorium)¶
| Time | Event |
|---|---|
| 9:30-10:00 | 📋 RegistrationRegister/coffee |
| 10:00-11:30 |
🎤 Invited TalksInvited speakers (25+5 min/talk): Session chairs: Mark Gorris, to be confirmed
Heather Melichar (McGill) Predicting T cell responses from intracellular calcium dynamics
Sonja Bushow (Erasmus MC) Immunopeptidomics in chronic HBV infection for therapeutic vaccine design
Ludger Klein (LMU Munich)
Role of B cells in central T cell tolerance
|
| 11:30-13:00 | 🍽️ LunchLunch and poster session |
| 13:00-14:30 |
🎤 Invited TalksInvited speakers (25+5 min/talk): Session chairs: to be confirmed
Mark Gorris (Radboudumc) Induction of Frameshift-specific T cells through Dendritic Cell Vaccination in Lynch Syndrome and CMMRD
Timo van den Berg (Byondis & Radboudumc, antibody therapy) Therapeutic targeting of the CD47-SIRPα myeloid immune checkpoint in cancer with the anti-SIRPα antibody BYON4228
Raquel Cuella Martin (McGill)
High-throughput precision gene editing to systematically characterize unusual protein-protein interactions
|
| 14:30-15:00 | ☕ BreakCoffee break |
| 15:00-16:15 |
🎤 Invited TalksInvited speakers (20+5 min/talk): Session chairs: to be confirmed
Alexandre Bonvin (Utrecht University) AI and physics-based integrative modelling of immune complexes
Anna Vangone (Roche) Drug discovery in the era of AI
Guang Yang (Shanghai Tech)
A broadly neutralizing antibody recognizing a unique epitope with a signature motif common across coronaviruses
|
| 16:15-16:45 | ☕ BreakCoffee break |
| 16:45-17:30 |
⚡ Flash TalksFlash talks (12+3 min/talk): Session chairs: to be confirmed
Thomas Kuilman (AstraZeneca) Establisment of a TCR Discovery Platform to support building ML models that predict TCR characteristics
Asima Abidi (Radboudumc) Characterization of TGF-BRII frameshift neoepitope specific T cell receptors for use in adoptive T cell therapy
Tom Hofland (Radboudumc)
Retrotransposable elements as novel cancer-specific antigens
|
| 17:30 | 🎯 ClosingClosing remarks |